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Imugene completes enrolment of first cohort of patients in Phase I clinical trial of checkpoint immunotherapy candidate PD1-Vaxx

Imugene Ltd (ASX:IMU) (OTCMKTS:IUGNF) has completed enrolment of the first cohort of patients in a Phase I clinical trial of its checkpoint immunotherapy candidate, PD1-Vaxx.
The clinical-stage immune-oncology company has enrolled the first three patients in the first low dose PD1-Vaxx cohort with non-small cell lung cancer.
Significant milestone
Imugene managing director and chief executive officer Leslie Chong said: "The start of our study with first patient dosed in Australia just 18 days ago was a significant milestone for Imugene and clinicians treating Australians faced with the challenge of lung cancer.
"I'm encouraged by the speed at which our Australian hospitals have recruited the first cohort of patients."
Three different doses of PD1-Vaxx to be tested
The first-in-human, Phase 1, multi-centre, dose-escalation study of PD1-Vaxx is recruiting patients with non-small cell lung cancer.
Medical investigators will test three different doses of PD1-Vaxx.
The primary goal of the Phase 1 trial is to determine safety and an optimal biological dose as a monotherapy (mOBD).
Efficacy, tolerability and immune response will also be measured.


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